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Date: 23-6-2016
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Date: 30-6-2018
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Date: 22-10-2020
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Because esters can contain α hydrogens they can undergo a condensation reaction similar to the aldol reaction called a Claisen Condensation. In a fashion similar to the aldol, one ester acts as a nucleophile while a second ester acts as the electrophile. During the reaction a new carbon-carbon bond is formed. The product is a β-keto ester. A major difference with the aldol reaction is the fact that hydroxide cannot be used as a base because it could possibly react with the ester. Instead, an alkoxide version of the alcohol used to synthesize the ester is used to prevent transesterification side products.
Example 1: Claisen Condensation
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اختبار دم يتنبأ بالإصابة بباركنسون قبل سنوات من ظهور الأعراض
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علماء يرصدون استيقاظ ثقب أسود هائل من سكونه
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العتبة العباسية تقدم دعوة لجامعة واسط لحضور فعاليات أسبوع الإمامة
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