Hemostasis  

Definition: Hemostasis is the maintenance of the clot-free state of blood & the prevention of blood loss via the formation of hemostatic plug. 

Hemostasis depends on three general components:

a) Vascular wall

b) Platelets

c) Coagulation pathways  

Whenever a vessel is ruptured or severed, hemostasis is achieved by several mechanisms: 

A.  Vascular spasm 

B.  Formation of platelet plug 

C.  Formation blood clot as a result of blood coagulation 

D.  Eventual growth of fibrous tissue in to the blood clot to close the hole in the vessel permanently.

References

Bezabeh ,M. ; Tesfaye,A.; Ergicho, B.; Erke, M.; Mengistu, S. and Bedane,A.; Desta, A.(2004). General Pathology. Jimma University, Gondar University Haramaya University, Dedub University.