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تسجيل

Antibiotic Susceptibility Testing and Therapy of Borrelia

المؤلف:  Patricia M. Tille, PhD, MLS(ASCP)

المصدر:  Bailey & Scotts Diagnostic Microbiology

الجزء والصفحة:  13th Edition , p542

2026-06-11

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 Currently there are no standardized methods and borreliae are difficult to culture; therefore, antimicrobial susceptibility testing is not routinely performed.

Several antibiotics, including tetracycline, are effective in treating relapsing fever. Doxycycline, amoxicillin, or cefuroxime and parenteral cephalosporins are drugs of choice during the first stage of Lyme disease. Broad spectrum cephalosporins, particularly ceftriaxone or cefotaxime, have been used successfully with patients who either fail initial treatment or present in later stages of the disease. Oral regimes are typically successful; however, in atrioventicular blocks, the patient may require IV therapy. Symptomatic treatment failures, particularly in patients with chronic Lyme disease, have been reported.